Biosynthesis of Prodigiosin, a Secondary Metabolite of Serratia marcescens

Biosynthesis of prodigiosin, a secondary metabolite of Serratia marcescens.

Prodigiosenes (prodigiosin and prodigiosin-like pigments) are known to be synthesized by only one genus of Eubacteriales and by two genera of Actinomycetales. Biosynthesis by Serratia marcescens occurs over a relatively narrow range of temperatures, although the bacteria grow over a broad range. When cultures of S. marcescens were incubated at 27 C in 1.0% casein hydrolysate, viable count and p...

Review of Prodigiosin, Pigmentation in Serratia marcescens

Prodigiosins, a family of natural red pigments characterized by a common pyrrolylpyrromethane skeleton, are produced by various bacteria that first characterized from Serratia marcescens. This pigment is a promising drug owing to its reported characteristics of having antifungal, immunosuppressive and anti-proliferative activity. From an industrial point of view to obtain optimal conditions to ...

Spray-dried Prodigiosin from Serratia marcescens As A colorant

Encapsulation technique via spray drying can be employed to enhance the natural pigment’s properties. In this study, spray-dried microparticles containing red pigment (prodigiosin) extracted from Serratia marcescens was produced using κcarrageenan and maltodextrin as encapsulation agents. The effect of spray-drying parameters on the encapsulation yield (EY), particle size and color intensity of...

The biosynthesis of prodigiosin, the tripyrrylmethene pigment from Bacillus prodigiosus (Serratia marcescens).

Inhibitory effect of polymyxin B on prodigiosin biosynthesis in Serratia marcescens.

Sir: Prodigiosin or prodigiosin-like antibiotic pigments are tripyrrole compounds synthesized by Serratia marcescens, Vibrio psychroerythrus, Pseudomonas magnesorubra and Alteromonas rubra as well as several genera of actinomycetes.1.2) Although the structures of several of the pigments are known, the site of localization and biosynthesis is less than clear.3,4) Studies of inhibition of prodigi...